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Insufficient sleep lowers resistance to common cold

Last Updated: 2009-01-12 16:01:21 -0400 (Reuters Health)

January 3, 2009

NEW YORK (Reuters Health) - People who get less than seven hours of sleep per night appear about three times as likely to develop respiratory illness following exposure to a cold virus as those who sleep eight hours or more, according to research published Monday.

"Experimental studies have demonstrated that sleep deprivation results in poorer immune function," Dr. Sheldon Cohen, at Carnegie Mellon University, Pittsburgh, and co-investigators explain. However, there is little direct evidence to back up the theory that sleep affects susceptibility to illness.

Cohen's team interviewed 153 men and women daily for 14 consecutive days regarding how many hours they slept per night, what percentage of their time in bed was spent asleep (what researchers call "sleep efficiency") and whether they felt rested. The study subjects were then quarantined and administered nasal drops containing the common-cold-causing rhinovirus.

Results showed that the less an individual slept, the more likely he or she was to develop a cold.

Lower sleep efficiency was also associated with developing a cold - men and women who spent less than 92 percent of their time in bed asleep were five and a half times more likely to become ill than those whose sleep efficiency was 98 percent or more.

Feeling rested was not associated with colds.

These data support seven to eight hours of sleep as "a reasonable target," the team concludes. However, "even a minimal habitual sleep disturbance (sleep losses of 2 percent to 8 percent, 10 to 38 minutes for an 8-hour sleeper) is associated with 3.9-times the risk of developing a cold."

SOURCE: Archives of Internal Medicine, January 12, 2009.

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